{"id":295,"date":"2023-02-13T10:27:19","date_gmt":"2023-02-13T09:27:19","guid":{"rendered":"https:\/\/guidecbd.greeneo.wassa-preprod.com\/?p=295"},"modified":"2023-05-11T14:55:18","modified_gmt":"2023-05-11T12:55:18","slug":"quest-ce-que-le-systeme-endocannabinoide","status":"publish","type":"post","link":"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/","title":{"rendered":"Qu’est-ce Que Le Syst\u00e8me Endocannabino\u00efde ?"},"content":{"rendered":"\n

Pour r\u00e9sumer, le syst\u00e8me endocannabino\u00efde est un groupe de lipides sp\u00e9cialis\u00e9s, leurs r\u00e9cepteurs et les enzymes les produisent et les d\u00e9gradent.<\/p>\n\n\n\n

Le remplacement des aliments transform\u00e9s riches en om\u00e9ga-6 (chips et pommes de terre sal\u00e9es) par des alternatives riches en om\u00e9ga-3 (par exemple, filet de saumon, sardine et l\u00e9gumes frais) am\u00e9liore la sant\u00e9 cardiovasculaire, la sant\u00e9 du cerveau et le bien-\u00eatre m\u00e9tabolique. Mais quel est le rapport avec le CBD et le syst\u00e8me endocanabino\u00efde<\/a> ? Suivez le guide et vous verrez pourquoi on peut utiliser cette analogie plut\u00f4t d\u00e9routante !<\/p>\n\n\n\n

QU\u2019EST-CE QUE LE SYST\u00c8ME ENDOCANNABINO\u00cfDE ?<\/h2>\n\n\n\n

Pour r\u00e9sumer, le syst\u00e8me endocannabino\u00efde est un groupe de lipides sp\u00e9cialis\u00e9s, leurs r\u00e9cepteurs et les enzymes les produisent et les d\u00e9gradent.<\/p>\n\n\n

\r\n \"D\u00e9couvrez\r\n \r\n D\u00e9couvrez nos Huiles CBD <\/a>\r\n<\/section>\r\n<\/div>\n\n\n

Par des actions directes et indirectes, les endocannabino\u00efdes sont connus pour moduler et influencer une vari\u00e9t\u00e9 de syst\u00e8mes physiologiques, notamment l\u2019app\u00e9tit, la douleur, l\u2019inflammation, la thermor\u00e9gulation, la pression intra-oculaire, la sensation, le contr\u00f4le musculaire, l\u2019\u00e9quilibre \u00e9nerg\u00e9tique, le m\u00e9tabolisme, la sant\u00e9 du sommeil, les r\u00e9ponses au stress, la motivation\/r\u00e9compense, l\u2019humeur et la m\u00e9moire.<\/p>\n\n\n\n

QU\u2019EST-CE QUE LES R\u00c9CEPTEURS CANNABINO\u00cfDES ?<\/h2>\n\n\n\n

Les r\u00e9cepteurs cannabino\u00efdes sont une importante classe de r\u00e9cepteurs de la membrane cellulaire qui sont \u00e9galement connus pour avoir une forme de bobine. Les r\u00e9cepteurs sont semblables \u00e0 des \u00ab serrures \u00bb, et les compos\u00e9s qui s\u2019y fixent sont semblables aux \u00ab cl\u00e9s \u00bb d\u2019un syst\u00e8me ouvert et ferm\u00e9. Ils comportent environ sept sections qui passent \u00e0 travers la membrane cellulaire externe. Les r\u00e9cepteurs cannabino\u00efdes sont \u00e9galement coupl\u00e9s aux prot\u00e9ines G, o\u00f9 une grande partie de la \u00ab magie \u00bb de la signalisation se produit lorsqu\u2019une mol\u00e9cule ou un compos\u00e9 se lie \u00e0 la partie externe de ces r\u00e9cepteurs.<\/p>\n\n\n\n

Les trois principaux liants des r\u00e9cepteurs de cannabino\u00efdes sont tous lipophiles (compos\u00e9s gras ou \u00ab similaires \u00bb), et comprennent les endocannabino\u00efdes (synth\u00e9tis\u00e9s dans l\u2019organisme), les phytocanabino\u00efdes (d\u00e9riv\u00e9s de plantes, comme le cannabis) et les cannabino\u00efdes synth\u00e9tiques. Les r\u00e9cepteurs de cannabino\u00efdes sont divis\u00e9s en deux sous-types principaux, appel\u00e9s CB1 et CB2. Bien qu\u2019elles pr\u00e9sentent certaines similitudes, elles se diff\u00e9rencient principalement par le syst\u00e8me de tissus ou d\u2019organes auquel elles sont associ\u00e9es dans l\u2019organisme. Concernant le CBD : le CB1 se trouve principalement dans le cerveau, avec une certaine pr\u00e9sence dans les poumons, les reins, le foie, la graisse, le c\u0153ur, les muscles et les os.<\/p>\n\n\n\n

Les r\u00e9cepteurs CB1 sont principalement associ\u00e9s aux aspects psychoactifs et euphoriques du THC. Cependant, les r\u00e9cepteurs CB2 se trouvent principalement dans le syst\u00e8me immunitaire et les cellules sanguines, et secondairement en plus faible densit\u00e9 dans le syst\u00e8me nerveux, le foie, l\u2019intestin, les muscles et les os.<\/p>\n\n\n\n

COMMENT LES R\u00c9CEPTEURS CANNABINO\u00cfDES CONTRIBUENT-ILS \u00c0 L\u2019\u00c9QUILIBRE DU SYST\u00c8ME ENDOCANNABINO\u00cfDE ?<\/h2>\n\n\n\n

L\u2019\u00e9quilibre endocannabino\u00efde est la contribution relative de l\u2019activit\u00e9 de CB1 vs CB2 \u00e0 un moment donn\u00e9. Les recherches s\u2019accumulent pour d\u00e9montrer que la dominance du CB1 est associ\u00e9e \u00e0 une perception accrue du stress, de l\u2019anxi\u00e9t\u00e9, de la parano\u00efa, \u00e0 un app\u00e9tit accru et \u00e0 une diminution des naus\u00e9es\/vomissements et de la douleur, ainsi qu\u2019\u00e0 une meilleure surveillance immunologique, cette derni\u00e8re \u00e9tant d\u00e9montr\u00e9e dans certains mod\u00e8les de cancer.<\/p>\n\n\n\n

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En revanche, la dominance du CB2 est associ\u00e9e \u00e0 une diminution de l\u2019inflammation et des l\u00e9sions tissulaires, ainsi qu\u2019\u00e0 des am\u00e9liorations de la sant\u00e9 m\u00e9tabolique, de la signalisation\/sensibilit\u00e9 \u00e0 l\u2019insuline, de la sati\u00e9t\u00e9 et de l\u2019\u00e9quilibre \u00e9nerg\u00e9tique.<\/p>\n\n\n\n

En utilisant ces informations, certains scientifiques se concentrent sur des bloqueurs CB1 sp\u00e9cifiques qui peuvent am\u00e9liorer de nombreux sympt\u00f4mes du syndrome m\u00e9tabolique. Le syndrome m\u00e9tabolique est un ensemble de facteurs de risque qui augmentent le risque de maladie cardiaque, d\u2019accident vasculaire c\u00e9r\u00e9bral et de diab\u00e8te.<\/p>\n\n\n\n

Sp\u00e9cifiquement, il comprend une augmentation de la pression sanguine, une augmentation du taux de sucre dans le sang, un exc\u00e8s de graisse autour de la taille et des taux de cholest\u00e9rol anormaux. Certaines recherches dans ce domaine ont montr\u00e9 que l\u2019inhibition p\u00e9riph\u00e9rique du CB1 r\u00e9duit la pression sanguine et le taux de sucre dans le sang et am\u00e9liore le taux de cholest\u00e9rol, en plus d\u2019entra\u00eener une perte de graisse visc\u00e9rale, ce qui se traduit par un risque plus faible de maladie cardiovasculaire et de diab\u00e8te de type II.<\/p>\n\n\n\n

QU\u2019EST-CE QUI FAIT UN SYST\u00c8ME ENDOCANNABINO\u00cfDE \u00c9QUILIBR\u00c9 ?<\/h2>\n\n\n\n

Des d\u00e9couvertes biochimiques et comportementales r\u00e9centes d\u00e9montrent que l\u2019activation \u00ab optimale \u00bb des r\u00e9cepteurs CB1 favorise des changements neurochimiques de type antid\u00e9presseur et des effets comportementaux compatibles avec l\u2019activit\u00e9 antid\u00e9presseur\/antistress chez les rongeurs. Ces r\u00e9sultats renforcent l\u2019importance d\u2019un syst\u00e8me endocannabino\u00efde \u00e9quilibr\u00e9. Il est connu pour contr\u00f4ler la prolif\u00e9ration, la diff\u00e9renciation, la survie et la comp\u00e9tence immunitaire du syst\u00e8me d\u2019organes t\u00e9gumentaires souvent n\u00e9glig\u00e9 (c\u2019est-\u00e0-dire les cellules de la peau et des cheveux). La segmentation et la manipulation de l\u2019\u00e9quilibre des endocannabino\u00efdes dans le but de normaliser la croissance ind\u00e9sirable des cellules de la peau et l\u2019inflammation cutan\u00e9e peuvent \u00eatre b\u00e9n\u00e9fiques pour diverses affections cutan\u00e9es humaines (psoriasis, ecz\u00e9ma, acn\u00e9, dermatite, scl\u00e9rose syst\u00e9mique, etc.)<\/p>\n\n\n\n

Que se passe-t-il lorsque le syst\u00e8me endocannabino\u00efde se d\u00e9s\u00e9quilibre ? Gardez \u00e0 l\u2019esprit que l’ \u00bb\u00e9quilibre \u00bb est essentiel, car des recherches ont montr\u00e9 que si nous faisons trop pencher la balance dans le sens de l\u2019inhibition du CB1, il peut y avoir une diminution de la fertilit\u00e9 associ\u00e9e \u00e0 un risque accru de d\u00e9pression, de troubles de l\u2019humeur et d\u2019immunosuppression. Une surabondance de signaux CB1 a \u00e9t\u00e9 associ\u00e9e \u00e0 une augmentation de la psychoactivit\u00e9, de l\u2019inflammation syst\u00e9mique, du risque cardiovasculaire, du diab\u00e8te et de l\u2019ob\u00e9sit\u00e9. En revanche, la surabondance et la dominance du CB2 peuvent entra\u00eener une diminution de la fonction immunitaire et une baisse de la cicatrisation des plaies.<\/p>\n","protected":false},"excerpt":{"rendered":"

Pour r\u00e9sumer, le syst\u00e8me endocannabino\u00efde est un groupe de lipides sp\u00e9cialis\u00e9s, leurs r\u00e9cepteurs et les enzymes les produisent et les d\u00e9gradent. Le remplacement des aliments transform\u00e9s riches en om\u00e9ga-6 (chips et pommes de terre sal\u00e9es) par des alternatives riches en om\u00e9ga-3 (par exemple, filet de saumon, sardine et l\u00e9gumes frais) am\u00e9liore la sant\u00e9 cardiovasculaire, la […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ghostkit_customizer_options":"","ghostkit_custom_css":"","ghostkit_custom_js_head":"","ghostkit_custom_js_foot":"","ghostkit_typography":"","footnotes":""},"categories":[51],"tags":[],"ppma_author":[32],"class_list":["post-295","post","type-post","status-publish","format-standard","hentry","category-les-effets-du-cbd","author-lionel-fr"],"yoast_head":"\nQu'est-ce Que Le Syst\u00e8me Endocannabino\u00efde ? - Greeneo Guide du CBD<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Qu'est-ce Que Le Syst\u00e8me Endocannabino\u00efde ? - Greeneo Guide du CBD\" \/>\n<meta property=\"og:description\" content=\"Pour r\u00e9sumer, le syst\u00e8me endocannabino\u00efde est un groupe de lipides sp\u00e9cialis\u00e9s, leurs r\u00e9cepteurs et les enzymes les produisent et les d\u00e9gradent. Le remplacement des aliments transform\u00e9s riches en om\u00e9ga-6 (chips et pommes de terre sal\u00e9es) par des alternatives riches en om\u00e9ga-3 (par exemple, filet de saumon, sardine et l\u00e9gumes frais) am\u00e9liore la sant\u00e9 cardiovasculaire, la […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/\" \/>\n<meta property=\"og:site_name\" content=\"Greeneo Guide du CBD\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/cbdgreeneo\" \/>\n<meta property=\"article:published_time\" content=\"2023-02-13T09:27:19+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-11T12:55:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/guidecbd.greeneo.wassa-preprod.com\/wp-content\/uploads\/2023\/05\/3700809031591_2-4-1024x1024.jpg\" \/>\n<meta name=\"author\" content=\"Lionel\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lionel\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/\"},\"author\":{\"name\":\"Lionel\",\"@id\":\"https:\/\/cbd-greeneo.com\/guide\/cbd\/#\/schema\/person\/9b60efe77757f326a41d791480684a0b\"},\"headline\":\"Qu’est-ce Que Le Syst\u00e8me Endocannabino\u00efde ?\",\"datePublished\":\"2023-02-13T09:27:19+00:00\",\"dateModified\":\"2023-05-11T12:55:18+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/\"},\"wordCount\":1114,\"publisher\":{\"@id\":\"https:\/\/cbd-greeneo.com\/guide\/cbd\/#organization\"},\"image\":{\"@id\":\"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/guidecbd.greeneo.wassa-preprod.com\/wp-content\/uploads\/2023\/05\/3700809031591_2-4-1024x1024.jpg\",\"articleSection\":[\"Les Effets Du CBD\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/\",\"url\":\"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/\",\"name\":\"Qu'est-ce Que Le Syst\u00e8me Endocannabino\u00efde ? 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Le remplacement des aliments transform\u00e9s riches en om\u00e9ga-6 (chips et pommes de terre sal\u00e9es) par des alternatives riches en om\u00e9ga-3 (par exemple, filet de saumon, sardine et l\u00e9gumes frais) am\u00e9liore la sant\u00e9 cardiovasculaire, la […]","og_url":"https:\/\/cbd-greeneo.com\/guide\/cbd\/quest-ce-que-le-systeme-endocannabinoide\/","og_site_name":"Greeneo Guide du CBD","article_publisher":"https:\/\/www.facebook.com\/cbdgreeneo","article_published_time":"2023-02-13T09:27:19+00:00","article_modified_time":"2023-05-11T12:55:18+00:00","og_image":[{"url":"https:\/\/guidecbd.greeneo.wassa-preprod.com\/wp-content\/uploads\/2023\/05\/3700809031591_2-4-1024x1024.jpg","type":"","width":"","height":""}],"author":"Lionel","twitter_card":"summary_large_image","twitter_misc":{"\u00c9crit par":"Lionel","Dur\u00e9e de lecture estim\u00e9e":"6 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